Pathology report:

Diagnosis

A: "Periareolar Lesion Right Breast": Fibroadipose breast tissue exhibiting focal histologic changes consistent with previous biopsy site (see #####) with focal ductal carcinoma in situ, comedo type (High Grade), and assocated microscopic focus (0.2 cm in greatest dimension) of moderately differentiated infiltrating ductal carcinoma (See Part B)

B: "Right Breast Mass": Fibroadipose Breast tissue exhibiging focal histological changes consistent with previous biopsy site (see #####) with focus of moderately differentiated infiltrating ductal carinoma measuring up to approximately 1.0 x .5 cm on slide, in a background of ductal carcinoma in situ, comedo type (high grade). Tumor Focally involves labeled edge of specimen.

Microscopic Description

A: Section revals fibroadipose breast tissue with focal intraductal prolferation of atypical cells. These cells have increased nuclear cytoplasmic ratios and hyperchromatic pleomorphic nuclei. Microscopic focus of infiltrating tumor is noted with these cells have hyperchromatic and pleomorphic nuclei. Tubule formation score is 3, nuclear pleomorphism score is 3, mitotic rate score is 2. Dr. ####### concurs.

B: Section reveals findings similar to those seen in part A. Central necrosis is noted in intraepithelial proliferations. ADditional, section B3 reveals infiltrating tumor with characteristics similar to those seen in part A. Tumor focally involves labeled edge of specimen. Dr. ###### concurs.